GHK-Cu Cream: Accelerating Injury Recovery and Tissue Repair

GHK-Cu Cream: Accelerating Injury Recovery and Tissue Repair

GHK-Cu cream, featuring the copper-binding tripeptide glycyl-L-histidyl-L-lysine (GHK-Cu), offers a targeted topical approach to enhance wound healing, reduce inflammation, and support regeneration after injuries. This naturally occurring peptide—found in human plasma, saliva, and urine—declines with age but stimulates collagen synthesis, angiogenesis, and tissue remodeling when applied topically at concentrations like 0.5% (5 mg/g).

Bottom line up front: GHK-Cu cream accelerates injury recovery by boosting collagen production, promoting new blood vessel growth, reducing oxidative stress, and improving overall tissue repair. Applied topically once or twice daily, it provides a non-invasive, localized option for wounds, strains, post-surgical healing, and skin-level injuries with strong evidence from animal and human studies.

What is GHK-Cu Cream?

GHK-Cu is a bioactive tripeptide that binds copper ions, enabling it to modulate gene expression for repair processes. Topical formulations (often 0.5% in creams) deliver it directly to the injury site, where it mimics the body's natural response to tissue damage. It attracts immune cells, stimulates fibroblasts, and regulates metalloproteinases for balanced remodeling—making it ideal for skin injuries, burns, ulcers, and even supporting deeper soft tissue recovery when applied over the area.

This aligns with regenerative protocols at IncreaseMyT, complementing systemic therapies for overall vitality and recovery.

How GHK-Cu Supports Injury Healing

GHK-Cu promotes multiple pathways in wound repair:

  • Collagen & ECM Production: Stimulates synthesis of collagen, elastin, and glycosaminoglycans for stronger tissue rebuilding.
  • Angiogenesis & Blood Flow: Enhances new blood vessel formation to deliver oxygen and nutrients to damaged areas.
  • Anti-Inflammatory & Antioxidant Effects: Reduces oxidative stress, inflammation, and cytokine activity for faster resolution.
  • Wound Closure Acceleration: Improves contraction, epithelialization, and granulation tissue formation—studies show 30-50% faster healing in various models.

Animal studies demonstrate systemic and local benefits, with topical application improving ischemic wounds, diabetic ulcers, and surgical sites. Human trials confirm enhanced skin repair, reduced wrinkles (as a proxy for remodeling), and better outcomes post-procedure.

Benefits for Specific Injuries

GHK-Cu cream shines for:

  • Skin Wounds & Cuts: Speeds closure and reduces scarring.
  • Post-Surgical Recovery: Supports graft take and reduces inflammation.
  • Sprains, Strains & Soft Tissue: Applied over the area to aid tendon/ligament remodeling and reduce fibrosis.
  • Chronic or Slow-Healing Injuries: Beneficial for ulcers or age-related delayed repair.

It offers a safe, localized alternative or adjunct to injectables like BPC-157/TB-500 for those preferring topicals.

To explore related recovery options, check our guide on peptides and longevity programs.

Application & Dosing – Simple & Effective

For 5 mg/g (0.5%) GHK-Cu cream:

  • Apply a thin layer (pea-sized to 0.5–2 grams, depending on area) to clean, dry skin over the injury.
  • Frequency: 1–2 times daily, gently massaging in.
  • Duration: Use for weeks to months, based on healing progress.

This delivers ~2.5–10 mg GHK-Cu per application—effective at low doses per studies. Patch test first; avoid open wounds unless directed.

Important: Protocols are individualized. Consult your provider for lab monitoring, exact dosing, and integration with other therapies. At IncreaseMyT, we prioritize the lowest effective dose for safety and results.

Your Next Step

At IncreaseMyT, we offer doctor-prescribed, evidence-informed regenerative options tailored to your labs and goals. GHK-Cu cream fits seamlessly into recovery-focused plans for injury healing and vitality.

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External References & Supporting Studies

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