Testosterone & Prostate Cancer Myth Debunked
In 1941 a single experiment on two castrated men created an 80-year fear that testosterone “feeds” prostate cancer. It took until 2009 for Dr. Abraham Morgentaler at Harvard to finally disprove it with the Saturation Model — and the last 15 years of clinical data have proven him right.
1941 – The Study That Started the Myth (Huggins & Hodges)
- Gave testosterone to just three previously castrated men with metastatic prostate cancer
- Two worsened dramatically → conclusion: “testosterone activates prostate cancer”
- Nobel Prize in 1966 cemented the idea for decades
Read the original 1941 paper →
Why That Study Doesn’t Apply to Normal Men
- Castrated men have massively upregulated androgen receptors (starving)
- Giving them testosterone is like pouring petrol on a fire
- Real-world TRT starts from low-normal, not zero
2009 – Morgentaler’s Saturation Model Changes Everything
Prostate growth is maximal at very low testosterone levels. Once T rises above ~250–300 ng/dL, the receptors saturate — adding more testosterone has almost no further effect.
Morgentaler & Traish, European Urology 2009 (Saturation Model) →
Modern Evidence (2015–2024) – TRT Is Safe in Every Scenario
Low Testosterone = Higher Risk of Aggressive Cancer
Dozens of studies now show men with low testosterone are significantly more likely to be diagnosed with high-grade, poorly differentiated tumors.
Review: Low T and aggressive prostate cancer →
Your Next Step
At IncreaseMyT we use the exact evidence-based protocols proven safe even in men with prostate cancer history. We don’t guess — we monitor labs and optimize you into the range shown to be protective.
Always consult your physician before beginning testosterone therapy.
